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实验诊断学_白细胞疾病的实验诊断

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  • 卷面总分:100分
  • 试卷类型:真题试卷
  • 测试费用:¥3.00
  • 试卷答案:有
  • 练习次数:1
  • 作答时间:30分钟

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实验诊断学_白细胞疾病的实验诊断

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  • 1男性,40岁。低热2个月余伴腹胀就诊。体检:T37.9℃,浅表淋巴结未触及,肝肋下2cm,脾肋下5cm。血常规:RBC5.5×1012/L,Hb122g/L,WBC125×109/L,分类示中性中幼粒细胞为10%,中性晚幼粒细胞为15%,中性杆状核粒细胞为30%,中性分叶核粒细胞为30%,嗜碱性分叶核粒细胞为2%,淋巴细胞为10%,单核细胞为3%,BPC550×109/L,NAP积分为0分。为明确诊断,应进行的检查不包括

    A.骨髓涂片检查

    B.染色体核型分析

    C.融合基因检查

    D.肝功能检查

    E.骨髓细胞培养

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  • 2造血幼稚细胞中有Auer小体,可见于

    A.巨幼细胞性贫血

    B.慢性白血病

    C.急性白血病

    D.急性淋巴细胞性白血病

    E.急性非淋巴细胞白血病

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  • 3The preferred site for bone marrow biopsy in an adult is the

    A.second intercostals space on the sternum

    B.any of the thoracic vertebrae

    C.anterior or posterior iliac crest

    D.anterior head of the femur

    E.skull

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  • 4The largest cell found in a normal bone marrow aspirate is the

    A.osteoblast

    B.megakaryocyte

    C.myeloblast

    D.pronormoblast

    E.metagranulocyte

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  • 5Immunologic phenotyping of the blast cells is important to

    A.help determine cell lineage

    B.identify the etiology of the leukemia

    C.determine if cytogenetic analysis is necessary

    D.replace the need to do multiple cytochemical stains

    E.replace the morphologic detection

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  • 6The FAB classification is used to divide acute leukemias into groups according to

    A.immunology

    B.clinical presentation

    C.cytogenetics

    D.morphology

    E.molecular phenotype

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  • 7Auer rods are inclusions found in

    A.myelobfasts

    B.lymphoblasts

    C.erythrocytes

    D.prolymphocytes

    E.megakaryocytes

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  • 8Chromosome changes in hematologic neoplasms are

    A.present in AL but not MPD or MDS

    B.nonrandom

    C.associated with a poor outcome

    D.not usually present

    E.associated with a good outcome

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  • 9A common characteristic of acute lymphocytic leukemia is

    A.a leukemia of older persons

    B.bone and joint pain

    C.many blast cells with Auer rods

    D.leykocytopenia

    E.many blast cells with positive POX stain

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  • 10A leukemia that shows a profusion of granulocytes at all stages of development,with the majority of cells being myelocytes and segmented neutrophils,is

    A.AML

    B.CML

    C.ALL

    D.CLL

    E.MDS

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